Non-Pulmonary Immune Functions of Surfactant Proteins A and D
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چکیده
منابع مشابه
Non-Pulmonary Immune Functions of Surfactant Proteins A and D.
Surfactant proteins A (SP-A) and D (SP-D) are established as essential components of our innate immune system for protecting the lung from pathogens and allergens. They essentially exert their protective functions by regulating pulmonary homeostasis. Both proteins are however widely expressed throughout the body, including the female reproductive tract, urinary tract, gastrointestinal tract, th...
متن کاملSurfactant proteins A and D.
30. Erdei, A. and Reid, K. B. M. (1989) Behring Inst. Mitt. 84,216-219 31. Malhotra, R., Thiel, S., Reid, K. B. M. and Sim, R. B. (1990) J. Exp. Med. 172,955-959 32. Malhotra, R.. Haurum, J.? Thiel, S. and Sim, R. B. (1 992) Eur. J. Immunol. 22,14371445 33. Guan, E., Burgess, W. H., Robinson, S. I+ Goodman, E. B., McTigue, K. H. and Tenner, A. J. (1991) J. Biol. Chem. 266,20345-20355 34. Priis-...
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Pulmonary surfactant proteins A and D enhance neutrophil uptake of bacteria.
The collectins are a class of collagenous lectin proteins present in serum and pulmonary secretions [pulmonary surfactant protein (SP) A and SP-D] that are believed to participate in innate immune responses to various pathogens. With the use of flow cytometric and fluorescent-microscopic assays, SP-A and SP-D were shown to increase calcium-dependent neutrophil uptake of Escherichia coli, Strept...
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ژورنال
عنوان ژورنال: Journal of Innate Immunity
سال: 2016
ISSN: 1662-811X,1662-8128
DOI: 10.1159/000451026